Standen MLB per 25 september
 | In New York wordt al teruggedacht aan het jaar 2000. Het was de laatste keer dat de Mets en Yankees in de World Series tegenover elkaar stonden. Deze week waren de twee ploegen de eersten die hun playoff-plaatsen veilig stelden. |
| American League | ||||||
| East Division | P | W | L | PCT | L10 | STRK |
| New York Yankees¹ | 155 | 93 | 62 | .600 | 4-6 | L2 |
| Boston Red Sox* | 156 | 83 | 73 | .532 | 5-5 | L2 |
| Toronto Blue Jays* | 155 | 82 | 73 | .529 | 7-3 | W2 |
| Baltimore Orioles* | 156 | 68 | 88 | .436 | 5-5 | L2 |
| Tampa Bay Devil Rays* | 155 | 60 | 95 | .387 | 3-7 | W2 |
| Central Division | P | W | L | PCT | L10 | STRK |
| Detroit Tigers² | 156 | 94 | 62 | .603 | 7-3 | W3 |
| Minnesota Twins | 155 | 92 | 63 | .594 | 7-3 | W2 |
| Chicago White Sox* | 156 | 87 | 69 | .558 | 3-7 | W2 |
| Cleveland Indians* | 155 | 72 | 83 | .465 | 4-6 | W2 |
| Kansas City Royals* | 155 | 58 | 97 | .374 | 3-7 | L6 |
| West Division | P | W | L | PCT | L10 | STRK |
| Oakland Athletics | 155 | 90 | 65 | .581 | 7-3 | L2 |
| Los Angeles Angels | 155 | 84 | 71 | .542 | 6-4 | W2 |
| Texas Rangers* | 156 | 78 | 78 | .500 | 4-6 | L2 |
| Seattle Mariners* | 156 | 75 | 81 | .481 | 6-4 | L2 |
| National League | ||||||
| East Division | P | W | L | PCT | L10 | STRK |
| New York Mets¹ | 155 | 93 | 62 | .600 | 3-7 | L1 |
| Philadelphia Phillies | 155 | 82 | 73 | .529 | 8-2 | W5 |
| Florida Marlins | 156 | 76 | 80 | .487 | 3-7 | L3 |
| Atlanta Braves* | 156 | 75 | 81 | .481 | 5-5 | L3 |
| Washington Nationals* | 155 | 68 | 87 | .439 | 5-5 | W1 |
| Central Division | P | W | L | PCT | L10 | STRK |
| St. Louis Cardinals | 154 | 80 | 74 | .519 | 3-7 | L5 |
| Houston Astros | 155 | 77 | 78 | .497 | 6-4 | W5 |
| Cincinnati Reds | 155 | 76 | 79 | .490 | 4-6 | W1 |
| Milwaukee Brewers* | 156 | 73 | 83 | .468 | 7-3 | W5 |
| Pittsburgh Pirates* | 156 | 65 | 91 | .417 | 5-5 | L4 |
| Chicago Cubs* | 156 | 63 | 93 | .404 | 5-5 | L1 |
| West Division | P | W | L | PCT | L10 | STRK |
| San Diego Padres | 155 | 83 | 72 | .535 | 7-3 | W4 |
| Los Angeles Dodgers | 156 | 82 | 74 | .526 | 5-5 | W1 |
| San Francisco Giants | 155 | 75 | 80 | .484 | 2-8 | L4 |
| Colorado Rockies* | 156 | 74 | 82 | .474 | 6-4 | W3 |
| Arizona Diamondbacks* | 155 | 73 | 82 | .471 | 5-5 | L1 |
| Situatie playoffs | |
| American League | |
| 1. | New York Yankees¹ |
| 2. | Detroit Tigers² |
| 3. | Oakland Athletics³ |
| 4. | Minnesota Twins |
| 5. | Chicago White Sox |
| National League | |
| 1. | New York Mets¹ |
| 2. | San Diego Padres³ |
| 3. | St. Louis Cardinals³ |
| 4. | Philadelphia Phillies |
| 5. | Los Angeles Dodgers |
| 6. | Houston Astros |
¹ Geplaatst als divisiekampioen
² Geplaatst; huidig divisieleider
³ Huidig divisieleider
* Geëlimineerd